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WASHINGTON – More than 2,000 criminal suspects died in police custody over a three-year period, half of them killed by officers as they scuffled or attempted to flee, the government said Thursday.

The study by the Justice Department’s Bureau of Justice Statistics is the first nationwide compilation of the reasons behind arrest-related deaths in the wake of high-profile police assaults or killings involving Abner Louima and Amadou Diallo in New York in the late 1990s.

The review found 55 percent of the 2,002 arrest-related deaths from 2003 through 2005 were due to homicide by state and local law enforcement officers. Alcohol and drug intoxication caused 13 percent of the deaths, followed by suicides at 12 percent, accidental injury at 7 percent and illness or natural causes, 6 percent. Causes of death for the remaining roughly 7 percent were unknown.

The highly populated states of California, Texas and Florida led the pack for both police killings and overall arrest- related deaths. Georgia, Maryland and Montana were not included in the study because they did not submit data.

Most of those who died in custody were men (96 percent) between the ages of 18 and 44 (77 percent). Approximately 44 percent were white; 32 percent black; 20 percent Hispanic; and 4 percent were of other or multiple races.

“Keep in mind we have 2,000 deaths out of almost 40 million arrests over three years, so that tells you by their nature they are very unusual cases,” said Christopher J. Mumola, who wrote the study.

“Still, they do need to be looked at to determine whether police training can be better or practices can be better,” he said.

State laws and police department policy typically let officers use deadly force to defend themselves or others from the threat of death or serious injury. Deadly force also is allowed to prevent the escape of a suspect in a violent felony who poses an immediate threat to others.

The Justice Department study released Thursday suggests that most of the police killings would be considered justified, although it does not make that final determination. About 80 percent involved suspects who reportedly brandished a weapon “to threaten or assault” officers.

Another 17 percent involved suspects who allegedly grabbed, hit or fought with police. More than one-third of the killings, or about 36 percent, involved a suspect who tried to flee or escape arrest.